1. Trials of phenanthrene opioids functionalization with hindered polycyclic carboxylic acids

Alessandro Venditti; Ambra Pallotti; Armandodoriano Bianco

Volume 3, Issue 3 , Summer 2019, , Pages 207-216

Abstract
  In the last decades, the number of patients undergoing pain relief for chronic or degenerative diseases has observed a significant increase, also due to an increase in the average age of the population. Morphine, the widely used opioid in pain therapy, is known to produce over time tolerance with the ...  Read More

Trials of phenanthrene opioids functionalization with hindered polycyclic carboxylic acids