Satureja myrtifolia (Boiss. & Hohen.) Lebanese wild plant, as a resource of natural antioxidants

Document Type: Original Article

Authors

1 Laboratoires Agronutition SAS, Parc Activestre 31390 Carbonne, France

2 Université Fédérale de Toulouse Midi-Pyrénées, INP-ENSIACET, Laboratoire de Chimie Agro-industrielle, Toulouse, France

Abstract

This study aims to evaluate total phenolic content (TPC) and in vitro antioxydant activity (AA) of S. myrtifolia collected from Lebanon. TPC of S. myrtifolia were extracted by two solvents (methanol and water) and determined spectrophotometrically. The AA of both crude extracts were evaluated in vitro by 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity method. Extracts exhibit relatively high levels of phenolic compounds which range from 343 ± 7.53 to 441 ± 10.70 mg GAE g-1 DW depending on the solvent used. Both extracts exerted hydrogen-donating ability in the presence of DDPH stable radical with a remarkable AA for aqueous extract. This study demonstrate that S. myrtifolia is a resource of biological active compounds which can reduces the risk of diseases and its effects which correlated with the antioxidant compounds.

Graphical Abstract

Satureja myrtifolia (Boiss. & Hohen.) Lebanese wild plant, as a resource of natural antioxidants

Keywords

Main Subjects


Adewoyin, M., Ibrahim, M., Roszaman, R., Isa, M.L.M., Alewi, N.A.M., Rafa, A.A.A., Anuar, M.N.N., 2017. Male infertility: The effect of natural antioxidants and phytocompounds on seminal oxidative stress. Diseases 5(1), 9.

Asmat, U., Abad, K., Ismail, K. 2016. Diabetes mellitus and oxidative stress - a concise review. Saudi Pharm. J. 24(5), 547-553.

Azmir, J., Zaidul, I.S.M., Rahman, M.M., Sharif, K.M., Mohamed, A., Sahena, F., Omar, A.K.M., 2013. Techniques for extraction of bioactive compounds from plant materials: a review. J. Food Eng. 117(4), 426-436.

Boulekbache-Makhlouf, L., Madani, K., 2014. Antioxidant capacity of crude extracts and their solvent fractions of selected Algerian Lamiaceae. Ind. Crop Prod. 52, 177-182.

Carikçi, S., 2016. The essential oil components of five Micromeria species grown in Anatolia. BAÜ Fen. Bil. Enst. Dergisi Cilt. 15(2), 73-79.

Ćavar, S., Vidic, D., Maksimović, M., 2013. Volatile constituents, phenolic compounds, and antioxidant activity of Calamintha glandulosa (Req.) Bentham. J. Sci. Food Agric. 93(7), 1758-1764.

Chang, S., Abbaspour, H., Nafchi, A.M., Heydari, A., Mohammadhosseini, M., 2016. Iranian Foeniculum vulgare essential oil and alcoholic extracts: Chemical composition, antimicrobial, antioxidant and application in olive oil preservation. J. Essent. Oil-Bear. Plants 19 (8), 1920-1931.

Dai, J., Mumper, R.J., 2010. Plant phenolics: Extraction, analysis and their antioxidant and anticancer properties.Molecules 15(10), 7313-7352.

Dobravalskyte, D., Venskutonis, P.R., Talou, T., 2012. Antioxidant properties and essential oil composition of Calamintha grandiflora L. Food Chem. 135(3), 1539-1546.

Dobravalskyte, D., Venskutonis, P.R., Talou, T., Zebib, B., Merah, O., Ragazinskiene, O., 2013. Antioxidant properties and composition of deodorized extracts of Tussilago farfara L. Rec. Nat. Prod. 7(3), 201.

Edris, A.E., 2007. Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: A review. Phytother. Res. 21(4), 308-323.

El Beyrouthy, M., Arnold, N., Delelis-Dusollier, A., Dupont, F., 2008. Plants used as remedies antirheumatic and antineuralgic in the traditional medicine of Lebanon. J. Ethnopharmacol. 120(3), 315-334.

Emami, S.A., Fakhrjafary, M., Tafaghodi, M., Hassanzadeh, M.K., 2010. Chemical composition and antioxidant activities of the essential oils of different parts of Cupressus arizonica Greene. J. Essent. Oil Res. 22(3), 193-199.

Eminagaoglu, O., Tepe, B., Yumrutas, O., Akpulat, H. A., Daferera, D., Polissiou, M., Sokmen, A., 2007. The in vitro antioxidative properties of the essential oils and methanol extracts of Satureja spicigera (K. Koch.) Boiss. and Satureja cuneifolia Ten. Food Chem. 100(1), 339-343.

Formisanoa, C., Oliviero, F., Riganoa, D., Saabb, A.M., Senatorea, F., 2014. Chemical composition of essential oils and in vitro antioxidant properties of extracts and essential oils of Calamintha origanifolia and Micromeria myrtifolia, two Lamiaceae from the Lebanon flora. Ind. Crop Prod. 62, 405-411.

Güllüce, M., Sökmen, M., Daferera, D., Aǧar, G., Özkan, H., Kartal, N., Şahin, F., 2003. In vitro antibacterial, antifungal, and antioxidant activities of the essential oil and methanol extracts of herbal parts and callus cultures of Satureja hortensis L. J. Agric. Food Chem. 51(14), 3958-3965.

Hajhashemi, V., Zolfaghari, B., Yousefi, A., 2011. Antinociceptive and anti-inflammatory activities of Satureja hortensis seed essential oil, hydroalcoholic and polyphenolic extracts in animal models. Med. Princ. Pract. 21(2), 178-182.

Hasani-Ranjbar, S., Bagher, L., Mohammad, A., 2009. A systematic review of the potential herbal sources of future drugs effective in oxidant-related diseases.  Curr. Drug Targets Inflamm. Allergy. 8(1), 2-10.

Hilan, C., Sfeir, R., Aitour, S., 2015. Chimiotypes de plantes communes au Liban du genre origanum et du genre Micromeria (Lamiaceae). Lebanease Sci. J. 12(1), 79-91.

Ignat, I., Volf, I., Popa, V.I., 2011. A critical review of methods for characterisation of polyphenolic compounds in fruits and vegetables. Food Chem. 126(4), 1821-1835.

Jothy, S.L., Zuraini, Z., Sasidharan, S., 2011. Phytochemicals screening, DPPH free radical scavenging and xanthine oxidase inhibitiory activities of Cassia fistula seeds extract. J. Med. Plants Res. 5(10), 1941-1947.

Khan, M. K., Dangles, O., 2014. A comprehensive review on flavanones, the major citrus polyphenols. J. Food Comp. Anal., 33(1), 85-104.

Kumar, S., Yadav, A., Yadav, M., Yadav, J.P., 2017. Effect of climate change on phytochemical diversity, total phenolic content and in vitro antioxidant activity of Aloe vera (L.) Burm.f. BMC Res. Notes 10(1), 60.

Miguel, M.G., 2010. Antioxidant activity of medicinal and aromatic plants. A review. Flav. Fragr. J. 25(5), 291-312.

Mohammadhosseini, M., 2016. Screening of the profiles of the essential oils from the aerial parts of Nepeta racemosa using classical and microwave-based methods: Comparison with the volatiles using headspace solid-phase micro-extraction. J. Herbal Drugs 7(2), 97-108.

Mohammadhosseini, M., Akbarzadeh, A., Hashemi-Moghaddam, H., 2016a. Gas chromatographic-mass spectrometric analysis of volatiles obtained by HS-SPME-GC-MS technique from Stachys lavandulifolia and evaluation for biological activity: A review. J. Essent. Oil-Bear. Plants 19(6), 1300-1327.

Mohammadhosseini, M., Akbarzadeh, A., Hashemi-Moghaddam, H., Shahnama, M., Fahimi, B., Azami, S., 2016b. Gas chromatographic-mass spectrometric analysis of volatiles obtained by HS-SPME-GC-MS technique from aerial parts of Ziziphora capitata L., and evaluation for biological activity. Oriental J. Chem. 32(3), 1439-1451.

Ozkan, G., Simsek, B., Kuleasan, H., 2007. Antioxidant activities of Satureja cilicica essential oil in butter and in vitro. J. Food Eng. 79(4), 1391-1396.

Rahimi, R., Ghiasi, S., Azimi, H., Fakhari, S., Abdollahi, M., 2010. A review of the herbal phosphodiesterase inhibitors; future perspective of new drugs. Cytokine 49(2), 123-129.

Raweh, S., Bayach, I., Taha, M., Baharudin, M.S., Di Meo, F., Hasan, M.H., Trouillas, P., 2013. Antioxidant properties of phenolic Schiff bases: structure-activity relationship and mechanism of action. J. Comput. Aided. Mol. Des., 27(11), 951.

Sánchez‐Moreno, C., Larrauri, J.A., Saura‐Calixto, F., 1998. A procedure to measure the antiradical efficiency of polyphenols. J. Sci. Food Agric., 76(2), 270-276.

Sánchez-Rangel, J.C., Benavides, J., Heredia, J.B., Cisneros-Zevallos, L., Jacobo-Velázquez, D.A., 2013. The Folin-Ciocalteu assay revisited: improvement of its specificity for total phenolic content determination. Anal. Methods 5(21), 5990-5999.

Schaich, K.M., Tian, X., Xie, J., 2015. Hurdles and pitfalls in measuring antioxidant efficacy: a critical evaluation of ABTS, DPPH, and ORAC assays. J. Funct. Foods 14, 111-125.

Sulaiman, S.F., Sajak, A.A.B., Ooi, K.L., Seow, E.M., 2011. Effect of solvents in extracting polyphenols and antioxidants of selected raw vegetables. J. Food Comp. Anal. 24(4), 506-515.

Xu, D.P., Li, Y., Meng, X., Zhou, T., Zhou, Y., Zheng, J., Li, H.B., 2017. Natural antioxidants in foods and medicinal plants: Extraction, assessment and resources. Int. J. Mol. Sci. 18(1), 96.

Zebib, B., El-Beyrouthy, M., Safi, C., Merah, O., 2015. Chemical composition of the essential oil of Satureja myrtifolia (Boiss. & Hohen.) from Lebanon. J. Essent. Oil-Bear. Plants 18(1), 248-254.